Cava, Bank of America, Fractyl Health

Wall Street's main indexes were mixed on Tuesday as investors awaited a crucial inflation report and other economic data that would offer further clues on the timing of rate cuts from the Federal Reserve and guide investor expectations.

At 13:33 ET, the Dow Jones Industrial Average DJI was down 0.41% at 38,910.21. The S&P 500 SPX was down 0.13% at 5,062.97 and the Nasdaq Composite IXIC was down 0.03% at 15,971.679.

The top three S&P 500 (.PG.INX) percentage gainers:

** Norwegian Cruise Line Holdings NCLH, up 16.8%

** Constellation Energy Corporation CEG, up 13.2%

** Carnival Corp CCL, up 7.4%

The top three S&P 500 (.PL.INX) percentage losers:

** SBA Communications SBAC, down 4.6%

** International Flavors & Fragrances IFF, down 3.4%

** Henry Schein HSIC, down 3.2%

The top three NYSE (.PG.N) percentage gainers:

** Gaotu Techedu GOTU, up 34.3%

** BigBear.ai Holdings BBAI, up 31.9%

** Hims & Hers Health HIMS, up 31.3%

The top three NYSE (.PL.N) percentage losers:

** Clarivate PLC CLVT, down 22.3%

** Oragenics OGEN, down 19.8%

** The Aaron's Company AAN, down 18.8%

The top three Nasdaq (.PG.O) percentage gainers:

** Janux Therapeutics JANX, up 209.7%

** Viking Therapeutics VKTX, up 112.8%

** CXApp CXAI, up 74.9%

The top three Nasdaq (.PL.O) percentage losers:

** Minerva Neurosciences NERV, down 58.5%

** Arisz Acquisition (ARIZ.O), down 39.6%

** Thoughtworks Holding TWKS, down 32.4%

** McDonald's Corp MCD: down 0.9%

** Domino's Pizza Inc DPZ: down 2.8%

BUZZ - Down after looming state inspections report

** Unity Software Inc U: down 8.4%

BUZZ - Piper Sandler expects Unity's 'reset' to kick in despite grim forecast

** Intuitive Machines Inc LUNR: down 11.3%

BUZZ - Tanks after Odysseus contact to be cut short

** Lowe's Companies Inc LOW: up 1.9%

BUZZ - Rises on smaller-than-expected Q4 sales decline

** Janux Therapeutics Inc JANX: up 209.7%

BUZZ - Surges on positive data from prostate cancer therapy trial

** iRobot Corp IRBT: down 1.8%

BUZZ - Drops on bigger-than-expected loss forecast

** Hims & Hers Health Inc HIMS: up 31.3%

BUZZ - Up on surprise Q4 profit, upbeat revenue forecast

** TransMedics Group Inc TMDX: up 13.3%

BUZZ - Jumps on upbeat annual revenue forecast

** Huntington Bancshares Inc HBAN: up 1.6%

BUZZ - Gains on D.A. Davidson upgrade to 'buy'

** Macy's Inc M: up 4.4%

BUZZ - Up as Q4 profit beat, to close 150 stores in new turnaround push

** Viking Therapeutics Inc VKTX: up 112.8%

BUZZ - Surges as weight-loss drug succeeds in mid-stage study

** MicroStrategy Inc MSTR: up 9.9%

BUZZ - Rises as brokerages lift PTs on additional bitcoin purchases

** Henry Schein Inc HSIC: down 3.2%

BUZZ - Falls on Q4 profit miss

** Hess Corp HES: down 3.2%

BUZZ - Falls as Exxon, Chevron in dispute over stake in Guyana oil block

** Norwegian Cruise Line Holdings Ltd NCLH: up 16.8%

BUZZ - Jumps on upbeat Q1 profit forecast, lifts peers

** Shift4 Payments Inc FOUR: up 3.8%

BUZZ - Reverses course as focus moves to strong 2024 outlook

** Constellation Energy Corp CEG: up 13.1%

BUZZ - Soars on upbeat 2024 profit forecast

** Delek US Holdings Inc DK: down 7.6%

BUZZ - Falls on bigger-than-expected Q4 loss

** American Electric Power Company Inc AEP: up 2.5%

BUZZ - Rises after CEO transition announced

** Minerva Neurosciences Inc NERV: down 58.5%

BUZZ - Slumps as FDA declines to approve schizophrenia drug

** AutoZone Inc AZO: up 5.1%

BUZZ - Rises after Q2 profit beat

** Kroger Co KR: up 2.6%

BUZZ - Up after Wells Fargo upgrades to 'equal weight', raises PT

** Roku Inc ROKU: down 1.4%

BUZZ - Falls as Wells Fargo downgrades to "underweight" on shifting competitive landscape

** Sezzle Inc SEZL: up 18.0%

BUZZ - Rises on Q4 profit jump

** Knight-Swift Transportation Holdings Inc KNX: down 1.9%

BUZZ - Falls after long-time CEO steps down

** Apollo Global Management Inc APO: down 0.2%

BUZZ - Dips after co-founder Leon Black sells stock

** EverQuote Inc EVER: up 0.6%

BUZZ - Jumps after strong Q1 revenue forecast

** Thoughtworks Holding Inc TWKS: down 32.4%

BUZZ - Tumbles on downbeat forecast, Q4 results miss

** Cava Group Inc CAVA: up 11.5%

BUZZ - Serves up Q4 rev beat, shares jump

** JPMorgan Chase & Co JPM: down 0.3%

BUZZ - Dips after CFO says trading revenue to decline in Q1

** Amgen Inc AMGN: down 2.0%

BUZZ - Down after Viking Therapeutics' weight-loss drug succeeds in mid-stage trial

** Bank of America Corp BAC: up 1.9%

BUZZ - Up after exec touts better-than-expected deposit trend

** Fractyl Health Inc GUTS: up 18.6%

BUZZ - Jumps as IPO research quiet period ends

** Vitesse Energy Inc VTS: up 4.8%

BUZZ - Climbs after Q4 core profit beat

The 11 major S&P 500 sectors: